Mechanical Signaling
Molecular Forces
This area of inquiry seeks to delineate the role of atomic and molecular forces to define mechanobiology at cellular levels. The process of force transmission through the lipid bilayer remains at best partially-understood and the nature of the forces developed and exerted at the cell or tissue level remain a fundamental area of inquiry.
Mechanosensitive Channels
Our center pursues close examination of the mechanisms associated with force form lipids signaling in excitable cells, where lipid-protein interaction define the function of many mechanosensitive channels, from prokaryotes to humans. Furthermore, a keen understanding of these forces and the molecular machines that underlie them will allow for the development of the mechanoelectrical building blocks required for future bioengineering developments.