Research

The main goal of our research is to decode the general mechanistic principles that relate function with protein movement, force transduction and its associated fluctuation dynamics.

The next frontier for us is to pioneer new technologies and approaches that elaborate the interplay between structure and its role in governing mechanical transduction, signaling and its role in complex biological phenomena (sensory physiology, development, signaling). Knowledge of how these fundamental phenomena control the mechanobiome function will be required to understand normal cellular physiology and pathophysiologic dysfunction.